Effects of the perceived temporal distance of events on mental time travel and on its underlying brain circuits.

Mental Time Travel (MTT) allows us to remember past events and imagine future ones. According to previous literature, the Temporal Distance of events affects MTT: our ability to order events worsens for close, compared to far, events. However, those studies established distances a-priori, albeit the way we perceive events' temporal distance may subjectively differ from their objective distance. Thus, in the current study, we aimed to investigate the effects of Perceived Temporal Distance (PTD) on the MTT ability and the brain areas mediating this process. Thirty-three healthy volunteers took part in an fMRI MTT task. Participants were asked to project themselves into the past, present, or future, and to judge a series of events as relative-past or relative-future, in relation to the adopted time location. Outside the scanner, participants provided PTD estimates for each stimulus of the MTT task. Participants' performance and functional activity were analyzed as a function of these estimations. At the behavioural level, PTD predicts the modulation of the performance for relative-past and relative-future. Bilateral angular gyrus, retrosplenial cortex, temporo-parietal region and medial, middle and superior frontal gyri mediate the PTD effect. In addition to these areas, the closer the relative-future events are perceived, the higher the involvement of left parahippocampal and lingual gyri and right cerebellum. Thus, perceived proximity of events activates frontal and posterior parietal areas, which therefore might mediate the processing of PTD in the cognitive spatial representation of time. Future proximity also activates cerebellum and medial temporal areas, known to be involved in imaginative and constructive cognitive functions.

Belonging matters: The impact of social identification with classmates, friends, and family on interpersonal distance and bullying/cyberbullying in adolescence.

In adolescence individuals enlarge their social relationships and peer groups acquire a strong importance for their identity. Moreover, adolescents can experiment negative relationships with peers, i.e., bullying/cyberbullying. The present study aims to investigate the relationship between the feeling of belonging to a specific group, social identification, the distance that adolescents maintain interacting with others, interpersonal distance, and bullying/cyberbullying behaviors. Adolescents (age range 10-15 years) completed online measures of group identification (social identification with classmates, friends and family), interpersonal distance, and bullying and cyberbullying (perpetration and victimization). Results showed that adolescents with low social identification with classmates and friends chose larger interpersonal distance. Additionally, low scores in social identification with classmates were associated with higher victimization in cyberbullying. In contrast, adolescents with low scores in social identification with family were more involved as bullies in bullying and as victims in cyberbullying. Male adolescents were more likely to be victimized in bullying than females. This study underlines how social identification with peers and family works as a buffer in interfacing strangers, adjusting the distance maintained with them, and as a protective factor against aggressive relationships in adolescence. This study provides new opportunities for psychologists in understanding the psychological dynamics that shape social interactions among adolescents.

Spatial attention modulation of the brain network involved in mental time travel.

OBJECTIVES: The ability to mental time travel (MTT) consists in moving along a cognitive and spatially oriented representation of time, that is, an ideal mental time line, where past and future events are, respectively, located on the left and on the right portion of such a line. A shift of spatial attention by prismatic adaptation (PA) influences this spatial coding of time, thus affecting MTT. Here, we investigated the neural correlates of such a spatial modulation on MTT in a functional Magnetic Resonance Imaging protocol. METHOD: To study MTT ability, participants were asked to indicate if a series of events took place before or after (Self-Reference component) an imagined self-location in time (Past, Present or Future; Self-Projection component), where they had to project themselves. The MTT task was performed before and after PA inducing a leftward shift of spatial attention, which is supposed to move toward the left portion of mental time line (MTL), where Past is represented. RESULTS: Following PA, we observed a facilitation in responding to past as compared to future events when participants projected themselves to the Past projection. As a functional counterpart of this behavioral finding, we propose a model of the brain activity modulations following the PA effects on MTT. CONCLUSIONS: As a result of the shift of spatial attention toward the left, the facilitation in having access to past events is associated with the inhibition of superior frontal gyrus in the left hemisphere, whereas the facilitation in projecting toward the Past may result from the activity modulation in right and left inferior parietal lobule. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Psychological Reactions during and after a Lockdown: Self-Efficacy as a Protective Factor of Mental Health.

The aim of the present study was to investigate the effects of home confinement/social isolation (i.e., lockdown), imposed to reduce large-scale spread of a disease in the population, on the mental health of individuals. Through an online survey during the lockdown (DL) related to COVID-19 (1085 respondents, 627 females, agerange: 18-82) (Italy, 23 April-2 May 2020), we revealed that situational factors, i.e., the presence of children at home and female gender, and psychological factors, i.e., a greater sense of isolation, lower perception of safety outside the home and higher trait anxiety, predicted higher levels of state anxiety (R2 = 0.58). The same factors, but with young age instead of the presence of children, predicted higher levels of perceived stress (R2 = 0.63). Then, these data were compared with those collected after the lockdown (AL) (174 respondents, 128 females, agerange: 19-78) (Italy, 1 July-31 October 2021). The results showed that along with a reduced sense of isolation (DL = 2.90 vs. AL = 2.10) and an increased perception of safety outside the home (DL = 2.63 vs. AL = 3.05), a reduction in state anxiety (DL = 45.76 vs. AL= 40.88) and stress appeared (DL = 18.84 vs. AL = 17.63). However, the situation was better for men than for women. Perceived self-efficacy emerged as a protective factor for mental health (R2range: 0.03-0.27). The results are discussed in light of the evidence on the effects of lockdown on individuals worldwide. These results may be used to make more educated decisions on targeted help for individuals who may be most adversely affected by the adoption of lockdowns in the future.

Time bisection and reproduction: Evidence for a slowdown of the internal clock in right brain damaged patients.

Previous studies show that the right hemisphere is involved in time processing, and that damage to the right hemisphere is associated with a tendency to perceive time intervals as shorter than they are, and to reproduce time intervals as longer than they are. Whether time processing deficits following right hemisphere damage are related and what is their neurocognitive basis is unclear. In this study, right brain damaged (RBD) patients, left brain damaged (LBD) patients, and healthy controls underwent a time bisection task and a time reproduction task involving time intervals varying between each other by milliseconds (short durations) or seconds (long durations). The results show that in the time bisection task RBD patients underestimated time intervals compared to LBD patients and healthy controls, while they reproduced time intervals as longer than they are. Time underestimation and over-reproduction in RBD patients applied to short but not long time intervals, and were correlated. Voxel-based lesion-symptom mapping (VLSM) showed that time underestimation was associated with lesions to a right cortico-subcortical network involving the insula and inferior frontal gyrus. A small portion of this network was also associated with time over-reproduction. Our findings are consistent with a slowdown of an 'internal clock' timing mechanism following right brain damage, which likely underlies both the underestimation and the over-reproduction of time intervals, and their (overlapping) neural bases.

The Role of Beta Oscillations in Mental Time Travel.

The brain processes short-interval timing but also allows people to project themselves into the past and the future (i.e., mental time travel [MTT]). Beta oscillations index seconds-long-interval timing (i.e., higher beta power is associated with longer durations). Here, we used parietal transcranial alternating current stimulation (tACS) to investigate whether MTT is also supported by parietal beta oscillations and to test the link between MTT and short intervals. Thirty adults performed a novel MTT task while receiving beta and alpha tACS, in addition to no stimulation. Beta tACS corresponded to a temporal underestimation in past but not in future MTT. Furthermore, participants who overestimated seconds-long intervals also overestimated temporal distances in the past-projection MTT condition and showed a stronger effect of beta tACS. These data provide a unique window into temporal perception, showing how beta oscillations may be a common mechanism for short intervals and MTT.

Bodily self-recognition in patients with pathological embodiment.

The ability to discriminate between one's own and others' body parts can be lost after brain damage, as in patients who misidentify someone else's hand as their own (pathological embodiment). Surprisingly, these patients do not use visual information to discriminate between the own and the alien hand. We asked whether this impaired visual discrimination emerges only in the ecological evaluation when the pathological embodiment is triggered by the physical alien hand (the examiner's one) or whether it emerges also when hand images are displayed on a screen. Forty right brain-damaged patients, with (E+ = 20) and without (E- = 20) pathological embodiment, and 24 healthy controls underwent two tasks in which stimuli depicting self and other hands was adopted. In the Implicit task, where participants judged which of two images matched a central target, the self-advantage (better performance with Self than Other stimuli) selectively emerges in controls, but not in patients. Moreover, E+ patients show a significantly lower performance with respect to both controls and E- patients, whereas E- patients were comparable to controls. In the Explicit task, where participants judged which stimuli belonged to themselves, both E- and E+ patients performed worst when compared to controls, but only E+ patients hyper-attributed others' hand to themselves (i.e., false alarms) as observed during the ecological evaluation. The VLSM revealed that SLF damage was significantly associated with the tendency of committing false alarm errors. We demonstrate that, in E+ patients, the ability to visually recognize the own body is lost, at both implicit and explicit level.

Right-deviating prismatic adaptation reduces obsessions in a community sample.

Background and aims: Patients with obsessive-compulsive (OC) disorder are impaired in disengaging attention from negative valence stimuli and show an attentional bias toward the right space. This pattern in OC disorder is similar to the impaired disengagement of attention from stimuli in the ipsilesional space as a consequence of a right-hemispheric cerebral lesion in patients with neglect, suggesting a right hemispheric dysfunction in patients with OC disorder. The attentional impairment in patients with neglect is reduced by a visuomotor procedure, such as prismatic adaptation (PA) with right-deviating lenses. Thus, here, we explored whether right-deviating PA is also effective in reducing OC psychological symptoms. Methods: Participants with a high rate of OC symptoms completed self-report measures of such symptoms before and after right- or left-deviating PA. Results: Right-deviating PA, and not left-deviating PA, reduced OC symptoms more prominently on obsessions than compulsions. Conclusion: Results support the idea that right-deviating PA might be considered an effective technique to modulate OC symptoms. This has implications for theories about the underlying mechanisms of OC symptoms and the consideration of PA as a complementary procedure to psychological treatments.

Space at home and psychological distress during the Covid-19 lockdown in Italy.

Prolonged periods of restrictions on people's freedom of movement during the first massive wave of the COVID-19 pandemic meant that most people engaged in all their daily activities at home. This suggested the need for the spatial features of the home and its occupants' perception of them to be investigated in terms of people's wellbeing. The present study was conducted on a large sample (N = 1354) drawn from different Italian regions. It examined the relationship between the "objective" and "subjective" dimensions of the home, measured in terms of objective home crowding and satisfaction with the space at home, in relation to perceived stress and the perceived risk of COVID-19 infection during the lockdown. The results showed that perceived stress is influenced by objective home crowding through the mediation of satisfaction with the space at home. These associations were more pronounced in younger generations. The negative association between satisfaction with the space at home and perceived stress was higher, the lower the perceived COVID-19 risk.

Social Distance during the COVID-19 Pandemic Reflects Perceived Rather Than Actual Risk.

Interpersonal space (IPS) is the area surrounding our own bodies in which we interact comfortably with other individuals. During the COVID-19 pandemic, keeping larger IPS than usual, along with wearing a face mask, is one of the most effective measures to slow down the COVID-19 outbreak. Here, we explore the contribution of actual and perceived risk of contagion and anxiety levels in regulating our preferred social distance from other people during the first wave of the COVID-19 pandemic in Italy. In this study, 1293 individuals from six Italian regions with different levels of actual risk of infection participated in an online survey assessing their perceived risk to be infected, level of anxiety and IPS. Two tasks were adopted as measures of interpersonal distance: the Interpersonal Visual Analogue Scale and a questionnaire evaluating interpersonal distance with and without face mask. The results showed that the IPS regulation was affected by how people subjectively perceived COVID-19 risk and the related level of anxiety, not by actual objective risk. This clarifies that the role of threat in prompting avoidant behaviors expressed in increased IPS does not merely reflect environmental events but rather how they are subjectively experienced and represented.

Neglect in temporal domain: Amelioration following a prismatic adaptation treatment and implications in everyday life. A single case study.

As in line bisection, in time bisection, neglect patients fail to process the first/left part of time representation (Mental-Time-Line-MTL) resulting in a rightward shift of the interval midpoint. A leftward shift of spatial attention after one session of prismatic-adaptation (PA) reduces this deficit. The impact on daily life of time deficit is little investigated in neglect. Here we study the time deficit and its ecological impact in an outpatient with neglect (LL) and the effects of a PA-treatment (ten sessions) on the deficit and its impact. Before and after PA-treatment, LL completed a: time-bisection-task assessing the MTL in the milliseconds-seconds range; lifespan-task assessing the MTL in the lifespan range; qualitative interview assessing the impact on daily routines. Patient's performance on the tasks was compared with the performance of non-neurological controls. Before PA-treatment, LL showed a rightward shift in the time-bisection-task and a compression of life events distribution in the lifespan-task. The feeling "to be forward in time" emerged in the interview. The PA-treatment reduced the deficits in the tasks and the feeling "to be forward in time" in the interview. PA-treatment is suggested as a powerful instrument for the reduction of time deficit and its ecological impact in neglect patients.

The physiological correlates of interpersonal space.

Interpersonal space (IPS) is the area around the body that individuals maintain between themselves and others during social interactions. When others violate our IPS, feeling of discomfort rise up, urging us to move farther away and reinstate an appropriate interpersonal distance. Previous studies showed that when individuals are exposed to closeness of an unknown person (a confederate), the skin conductance response (SCR) increases. However, if the SCR is modulated according to participant's preferred IPS is still an open question. To test this hypothesis, we recorded the SCR in healthy participants when a confederate stood in front of them at various distances simulating either an approach or withdrawal movement (Experiment 1). Then, the comfort-distance task was adopted to measure IPS: participants stop the confederate, who moved either toward or away from them, when they felt comfortable with other's proximity (Experiment 2). We found higher SCR when the confederate stood closer to participants simulating an IPS intrusion, compared to when the confederate moved farther away. Crucially, we provide the first evidence that SCR, acting as a warning signal, contributes to interpersonal distance preference suggesting a functional link between behavioral components of IPS regulation and the underlying physiological processes.

Neural Correlates of Interpersonal Space Permeability and Flexibility in Autism Spectrum Disorder.

Previous research indicates that the size of interpersonal space at which the other is perceived as intrusive (permeability) and the ability to adapt interpersonal distance based on contextual factors (flexibility) are altered in Autism Spectrum Disorder (ASD). However, the neurophysiological basis of these alterations remains poorly understood. To fill this gap, we used fMRI and assessed interpersonal space preferences of individuals with ASD before and after engaging in cooperative and non-cooperative social interactions. Compared to matched controls, ASDs showed lower comfort in response to an approaching confederate, indicating preference for larger interpersonal space in autism (altered permeability). This preference was accompanied by reduced activity in bilateral dorsal intraparietal sulcus (dIPS) and left fusiform face area (FFA), regions previously shown to be involved in interpersonal space regulation. Furthermore, we observed differences in effective connectivity among dIPS, FFA, and amygdala in ASDs compared to controls, depending on the level of experienced comfort. No differences between groups were observed in interpersonal space regulation after an experienced social interaction (flexibility). Taken together, the present findings suggest that a dysregulation of the activity and connectivity of brain areas involved in interpersonal space processing may contribute to avoidance of physical proximity and social impairments in ASD.

Time Interaction With Two Spatial Dimensions: From Left/Right to Near/Far.

In this study, we explored the time and space relationship according to two different spatial codings, namely, the left/right extension and the reachability of stimulus along a near/far dimension. Four experiments were carried out in which healthy participants performed the time and spatial bisection tasks in near/far space, before and after short or long tool-use training. Stimuli were prebisected horizontal lines of different temporal durations in which the midpoint was manipulated according to the Muller-Lyer illusion. The perceptual illusory effects emerged in spatial but not temporal judgments. We revealed that temporal and spatial representations dynamically change according to the action potentialities of an individual: temporal duration was perceived as shorter and the perceived line's midpoint was shifted to the left in far than in near space. Crucially, this dissociation disappeared following a long but not short tool-use training. Finally, we observed age-related differences in spatial attention which may be crucial in building the memory temporal standard to categorize durations.

Embodying an invisible face shrinks the cone of gaze.

The possibility of being invisible has long fascinated people. Recent research showed that multisensory illusions can induce experiences of bodily invisibility, allowing the psychological consequences of invisibility to be explored. Here, we demonstrate an illusion of embodying an invisible face. Participants received touches on their face and simultaneously saw a paintbrush moving synchronously in empty space and defining the shape of an invisible face. Using both explicit questionnaire measures (Experiment 1) and implicit physiological measures (Experiment 2), we show that such invisible enfacement induces a sense of ownership. We further demonstrate that embodying an invisible face shrinks the width of the cone of gaze (i.e., the range of eye deviations people judge as directed toward themselves; Experiments 3 and 4). These results suggest that the experience of invisibility affects the way in which we process the attention of others toward the self, starting from the perception of gaze direction. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

An asymmetry in past and future mental time travel following vmPFC damage.

The role of ventromedial prefrontal cortex (vmPFC) in mental time travel toward the past and the future is debated. Here, patients with focal lesions to the vmPFC and brain-damaged and healthy controls mentally projected themselves to a past, present or future moment of subjective time (self-projection) and classified a series of events as past or future relative to the adopted temporal self-location (self-reference). We found that vmPFC patients were selectively impaired in projecting themselves to the future and in recognizing relative-future events. These findings indicate that vmPFC damage hinders the mental processing of and movement toward future events, pointing to a prominent, multifaceted role of vmPFC in future-oriented mental time travel.

Me, you, and our object: Peripersonal space recruitment during executed and observed actions depends on object ownership.

Peripersonal space (PPS) is a spatial representation that codes objects close to one's own and to someone else's body in a multisensory-motor frame of reference to support appropriate motor behavior. Recent theories framed PPS beyond its original sensorimotor aspects and proposed to relate it to social aspects of the self. Here, we manipulated the ownership status of an object ("whose object this is") to test the sensitivity of PPS to such a pervasive aspect of society. To this aim, we assessed PPS through a well-established visuo-tactile task within a novel situation where we had dyads of participants either grasping or observing to grasp an object, whose ownership was experimentally assigned to either participant (individual ownership), or to both participants (shared ownership). When ownership was assigned exclusively ("this belongs to you/the other," Experiment 1), the PPS recruitment emerged when grasping one's own object (I grasp my object), as well as when observing others grasping their own object (you grasp your object). Instead, no PPS effect was found when grasping (and observing to grasp) an object that was not one's own (I grasp yours, you grasp mine). When ownership was equally assigned ("this belongs to both of you," Experiment 2), a similar PPS recruitment emerged and, again, both when the action toward the shared object was executed and merely observed. These findings reveal that ownership is critical in shaping relatively low-level aspects of body-object interactions during everyday simple actions, highlighting the deep mark of ownership over social behavior. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Spatial attention and representation of time intervals in childhood.

Spatial attention and spatial representation of time are strictly linked in the human brain. In young adults, a leftward shift of spatial attention by prismatic adaptation (PA), is associated with an underestimation whereas a rightward shift is associated with an overestimation of time both for visual and auditory stimuli. These results suggest a supra-modal representation of time left-to-right oriented that is modulated by a bilateral attentional shift. However, there is evidence of unilateral, instead of bilateral, effects of PA on time in elderly adults suggesting an influence of age on these effects. Here we studied the effects of spatial attention on time representation focusing on childhood. Fifty-four children aged from 5 to 11 years-old performed a temporal bisection task with visual and auditory stimuli before and after PA inducing a leftward or a rightward attentional shift. Results showed that children underestimated time after a leftward attentional shift either for visual or auditory stimuli, whereas a rightward attentional shift had null effect on time. Our results are discussed as a partial maturation of the link between spatial attention and time representation in childhood, due to immaturity of interhemispheric interactions or of executive functions necessary for the attentional complete influence on time representation.

The plasticity of the interpersonal space in autism spectrum disorder.

In recent years, there has been a dramatic increase in research examining interpersonal space, i.e., the sector of space immediately around the body in which we interact with other people. These studies have consistently revealed impairments of interpersonal space regulation in psychopathological disorders characterized by social disability, such as autism, schizophrenia and social anxiety. The primary goal of this review is to discuss several key points that have emerged in research on interpersonal space regulation in autism spectrum disorders. Particularly, we review recent behavioral evidence revealing that individuals with autism prefer abnormally larger or shorter interpersonal distance than healthy controls, indicating a deficit in regulating the size of interpersonal space (permeability). Then, we focus on how individuals with autism fail to modify their interpersonal space following a brief cooperative interaction with an unfamiliar adult, suggesting a deficit in adapting interpersonal space to the social context (plasticity). Moreover, we discuss evidence indicating that space regulation deficits primarily affect interpersonal (i.e., social), but not peripersonal (i.e., action), space in autism. Finally, we take into consideration the variables influencing interpersonal space plasticity such as person's perspective and severity of social impairment as well as its neural underpinnings. These findings may provide a critical contribution to understanding of the functional mechanisms underlying interpersonal space regulation and its rehabilitation in autism spectrum disorders.